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Omnica Laboratories

Cortilone 10mg Tab

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CORTILONE 10MG Tablet is a corticosteroid which is used to relieve inflammation in conditions like arthritis and allergic disorders. Use with caution in the patients with diabetes and other kidney diseases. Do not stop taking this medicine suddenly as it may cause confusion and headache.

 

Indications:

  • Gouty arthritis
  • Psoriasis
  • Nephrotic syndrome
  • Rheumatoid Arthritis
  • Asthma, wheezing, cough, difficulty in breathing 

Dosage:

  • ADULTS: 20-40mg daily (acute conditions up to 80mg daily) reducing gradually to maintenance level when symptoms have subsided. Maintenance dosage is usually 5-20mg daily reached in about two weeks by reduction of the daily dosage by 5mg or 2.5mg, two or three times a week.
  • PAEDIATRIC: Corticosteroids cause growth retardation in infancy, childhood and adolescence which may be irreversible. In order to minimise suppression of the hypothalamo-pituitary adrenal axis and growth retardation, treatment should be administered where possible as a minimum single dose on alternate days for the shortest possible time.
  • ELDERLY: Treatment of elderly patients, especially if long-term, should be planned bearing in mind the more serious consequences of the common side-effects of corticosteroids in old age, particularly diabetes, hypertension, hypokalaemia, osteoporosis, susceptibility to infection and thinning of the skin. Close clinical supervision is required to avoid life-threatening reactions. In general, initial dosage shall be maintained or adjusted until the anticipated response is observed. The dose should be gradually reduced until the lowest dose which will maintain an adequate clinical response is reached. Use of the lowest effective dose may also minimise side-effects.

Onset of Action: The peak effect of this medicine is observed within 5 minutes after an intravenous dose and 1 hour after an oral dose.

Duration of Action: The effect of this medicine lasts for a duration of 8 to 9 hours.

 

Side Effects:

  • Aggression or anger
  • Blurred vision
  • Decreased urine output
  • Dizziness
  • Headache
  • Weight gain
  • Fast heartbeat
  • Increased appetite

Interactions:

  1. Interaction with Medicines: Moderate to severe Interaction with Ethinyl Estradiol, Azole antifungal agents, Antihypertensives, Nonsteroidal anti-inflammatory drugs, Fluoroquinolone.
  2. Interaction with Diseases:
    Gastro-intestinal bleeding: It is used with caution in the patients with gastrointestinal diseases. The risk of bleeding is more when taken for a long duration of time. Dose adjustments are to be made based on the clinical condition.
    > Diabetes: It is used with caution in the patients with diabetes as it increases the blood glucose levels. Regular monitoring of blood glucose levels is necessary. A suitable antidiabetic agent should be prescribed based on the clinical condition.
  3. Interaction with Foods: Information not available.

 

Contraindications:

  • Allergy: Avoid if you have a known allergy to prednisolone or any other glucocorticoids.
  • Systemic infections: Avoid if you have any fungal or eye infections.

Warnings:

  • Infections: Use with caution in the patients who are at risk of developing infections. The severity of infections will increase with an increase in the dose. This medicine is not recommended in the patients with systemic fungal infection.
  • Vaccination: It may decrease the effect of live or attenuated vaccines. This medicine is not recommended in patients who are on vaccination.
  • Diabetes: It may increase the blood glucose levels and worsen the symptoms of diabetes. Use with caution in the patients with diabetes and dose adjustments are to be made based on the clinical condition.
  • Gastrointestinal diseases: It is used with caution as it may increase the risk of gastrointestinal disturbances like bleeding and abdominal distention.
  • Impaired kidney function: It may increase the water level in the body. Use with caution in the patients with the kidney injury and heart diseases. Frequent monitoring of kidney function tests is necessary.
  • Impaired liver function: It is used with caution in the patients with liver injury. The risk may increase if high-dose systemic corticosteroids are used. Frequent monitoring of liver function tests is necessary.
  • Decrease bone density It may decrease the bone density by decreasing the absorption of calcium. Use with caution in the postmenopausal women due to the risk of developing bone injuries.
  • Pregnancy: This medicine is recommended for pregnant women only if clearly needed and if no other safer alternative is available.
  • Lactation: This medicine is known to be excreted through breast milk in small amounts. Use this medicine only if clearly needed when no other safer alternative is available.
  • Safety with alcohol: Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

General Instructions:

  • You should carefully follow all instructions on the label.
  • The duration and amount of medicine consumed should be as prescribed by the doctor.
  • It can be taken with food or after food.
  • An adequate amount of water should be consumed to minimize the irritation caused in the stomach.

Storage Conditions:

  • Follow storage instructions on the product package if available.
  • Store tablet at room temperature 20-25ºC (68-77ºF), away from moisture, and away from light.
  • Store this medicine away from children and pets.

Substitutes:

Disclaimer
The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of the physician or other qualified health provider with any question you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.
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